Overview

XEO provides clients access to a full array of advanced analytical technologies, pre-formulation and drug development services.

 

Preformulation Screening

  • Chemical purity analysis

  • Physicochemical properties

  • Solid form definition and analysis

  • Molecular structure analysis

  • Excipient compatibility testing

  • Amorphous vs. crystalline solid state testing

  • Aqueous and solvent solubility

  • Solution and solid state stability

  • Vehicle screening for ADME and toxicity

 

Drug Development

NANOPARTICLE ENGINEERING SERVICES: SOLID LIPID NANOPARTICLES (SLNP), LIPOSOMES AND PROTEOLIPOSOMES, ETHOSOMES, MICELLES, EMULSIONS, AND POLYMERIC PARTICLES

NANOPARTICLE ENGINEERING METHODS: SIMPLE MIXING, EXTRUSION, SOLVENT EVAPORATION/PRECIPITATION, SONICATION AND HOMOGENIZATION, AND MICROFLUIDIZATION

NANOPARTICLE CHARACTERIZATION: PARTICLE SIZING (DLS), IMAGING (CONFOCAL AND SEM), DRUG ENTRAPMENT, DRUG RELEASE/LEAKAGE, DRUG ACTIVITY TESTING, STABILITY TESTING

PARENTERAL FORMULATION DEVELOPMENT: EXCIPIENT SELECTION, CONTAINER CLOSURE SELECTION AND INTEGRITY, EXTRACTABLES AND LEACHABLES, EXTENDED RELEASE FORMULATIONS, LYOPHILIZATION AND SPRAY DRYING


Equipment

  • Benchtop lyophilizer

  • Spray dryer

  • Environmental stability chambers

  • Homogenizer

  • Overhead Mixer

  • HPLC-MS

  • Dynamic Light Scanning 

  • Viscometer

  • Rheometer

  • Karl Fischer

  • Extruder for liposomes

  • And More. We have direct access to a variety of equipment that can be used to support all projects.